Find and Offer Help During Self Isolation

Get Involved
I need help
I can help
Amber A
United States
Added: 05.04.2020

I haven’t ben able to go to the gym because of the virus, and so I’m looking for someone to lead me through work-outs through Skype or some other video platform. Trying to stay accountable.

See details
Share on Facebook
Tweett
Ethel Frye
United States
Added: 03.04.2020

My grandma is 82 years old. She lives alone, her sight is weak, and she can’t cook anymore. I am stuck in London on quarantine, so I am very nervous about her well-being and mental state. She is now staying at home in Norfolk, VA. I am looking for someone to cook her a nice meal, deliver it, and have a little warm chat with my granny. All of the items will be paid for separately.

See details
Share on Facebook
Tweett
Alice C. Lambert
United States
Added: 03.04.2020

Hello, I am a 67 years old woman living in Union County, New Jersey, and I must confess, I am really feeling the brunt of this quarantine. I have had a series of medical conditions over the last few years that have left me confined to a wheelchair and left my health, not at 100 percent.

I’m quickly running low on my meds and other home supplies, and I’m seriously terrified of going out to get some, as I have learned that older people are more likely to experience fatal complications from the Covid-19 Virus.

I am alone and well right now, but in need of quick help. I need someone who can regularly help with my shopping; this will include my medication, groceries, and other home supplies. I’ll be most grateful.

See details
Share on Facebook
Tweett

Find Help

Access highly rated helpers that want to help you during your self-isolating.

Offer Help

Tell about how you could help people to stay at home during their quarantine.

Post for free

Post jobs for free to connect with people in your area and help each other.

Coronavirus surface proteins

Coronavirus ‘spike’ protein just mapped, leading way to vaccine | Live Science. Revealed: Protein 'spike' lets the 2019-nCoV coronavirus pierce, invade human cells - Get smart. Sign up for our email newsletter. Interest in this family of viruses grew in the aftermath of this epidemic, leading to the identification of many new family members.. Since the sequences of the E proteins are quite divergent, it will be interesting to determine if different CoV E proteins interact with the same host proteins, or are able to elicit a similar effect through interactions with other proteins. Coronaviruses are able to exploit many cell surface molecules—proteins and carbohydrates alike—in order to gain entry into target cells. The infectious bronchitis virus coronavirus envelope protein alters Golgi pH to protect spike protein and promote release of infectious virus. Unfortunately, they didn't work. The large size and replication strategy of the coronavirus genome also allows for frequent homologous recombination, a process that enables exchange of genetic material during co-infection. Biochemical and functional characterization of the membrane association and membrane permeabilizing activity of the severe acute respiratory syndrome coronavirus envelope protein. The hydrophobic TMD of E is also crucial to the 2 release of virions [ 40 , 53 , ].

This is the same human receptor protein targeted by the earlier SARS coronavirus. But, disturbingly, the researchers found that nCoV binds to ACE2 with much higher affinity ( times Author: Jianling Xie. May 27,  · The PDZ domain is a protein-protein interaction module that can bind to the C-terminus of target proteins such as the cellular adapter proteins involved in host-cell processes important for viral infection [83,84,85,86].Cited by: Mar 08,  · The E protein, along with N, S, and M, are the major coronavirus structural proteins (Figure 1 A,B). The N protein is a soluble protein and packages the RNA genome to form the nucleocapsid. The S protein has a single transmembrane domain, is found in the virion envelope, and serves as the attachment and fusion www.qarantino.com by: coronavirus biology

Coronavirus envelope protein: current knowledge | Virology Journal | Full Text. Coronavirus - 1. Introduction This representation, shows the trimeric coronavirus biology and monomeric forms of the protein and is based on the three-dimensional predicted model found in the PDB database PDB entry 1T7G, coronavirus surface proteins ]. The authors would like to thank Bianca Gordon for proofreading the draft and providing valuable feedback as well as Tracey Calvert-Joshua for insight into the protein topology prediction programs. Coronavirus pseudoparticles formed with recombinant M and E proteins induce alpha interferon synthesis by leukocytes. Unique and conserved features of genome and coronavirsu of SARS-coronavirus, an early split-off from the coronavirus biology group 2 lineage. Furthermore, the authors found that inoculation of UCD1 to FCWF cells in the presence of competing heparin severely diminished infection.