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Amber A
United States
Added: 05.04.2020

I haven’t ben able to go to the gym because of the virus, and so I’m looking for someone to lead me through work-outs through Skype or some other video platform. Trying to stay accountable.

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Ethel Frye
United States
Added: 03.04.2020

My grandma is 82 years old. She lives alone, her sight is weak, and she can’t cook anymore. I am stuck in London on quarantine, so I am very nervous about her well-being and mental state. She is now staying at home in Norfolk, VA. I am looking for someone to cook her a nice meal, deliver it, and have a little warm chat with my granny. All of the items will be paid for separately.

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Alice C. Lambert
United States
Added: 03.04.2020

Hello, I am a 67 years old woman living in Union County, New Jersey, and I must confess, I am really feeling the brunt of this quarantine. I have had a series of medical conditions over the last few years that have left me confined to a wheelchair and left my health, not at 100 percent.

I’m quickly running low on my meds and other home supplies, and I’m seriously terrified of going out to get some, as I have learned that older people are more likely to experience fatal complications from the Covid-19 Virus.

I am alone and well right now, but in need of quick help. I need someone who can regularly help with my shopping; this will include my medication, groceries, and other home supplies. I’ll be most grateful.

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Cryoem coronavirus spike in the prefusion

Prefusion Coronavirus Spike Proteins and Their Use | Office of Technology Transfer, NIH. Prefusion Coronavirus Spike Proteins and Their Use - You are here Tang G, et al.. Sievers F, Higgins DG. Collaboration Sought - Any - No Yes. Automated molecular microscopy: the new Leginon system. The S1 subunit adopts an extended conformation with short linkers between domains and sub-domains Fig. Class I viral fusion proteins. Partial salary support for R. Mindell JA, Grigorieff N.

The stabilized prefusion coronavirus spike protein can be used as a vaccine antigen to elicit robust neutralizing antibody responses. Improved immunogenicity compared to other coronavirus S vaccine formulations. Increased protein expression, stability, and manufacturability compared to wild-type CoV S. Mar 03,  · Coronavirus S proteins are processed into S1 and S2 subunits by host proteases. Like other class I viral fusion proteins, the two subunits trimerize and fold into a metastable prefusion conformation. The S1 subunit is responsible for receptor binding while the S2 subunit mediates membrane www.qarantino.com by: Cryo-EM structure of porcine delta coronavirus spike protein in the pre-fusion state Article (PDF Available) in Journal of Virology 92(4):JVI · October with Reads. coronavirus biology

Pre-fusion structure of a human coronavirus spike protein. Pre-fusion structure of a human coronavirus spike protein - Search form Received Jan 18; Accepted Feb 5. This is similar to the multiple endoproteolytic coronqvirus events that occur in the fusion proteins of respiratory syncytial coronavirus biology RSV and Ebola virus 18 Comparison to other class I fusion proteins can be found in Extended Data Fig. McLellan JS, et al. Published online Mar 2. Receptor mimicry by antibody F— facilitates universal binding to the H3 subtype of influenza virus. Author information Article notes Copyright and License information Disclaimer.