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Amber A
United States
Added: 05.04.2020

I haven’t ben able to go to the gym because of the virus, and so I’m looking for someone to lead me through work-outs through Skype or some other video platform. Trying to stay accountable.

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Ethel Frye
United States
Added: 03.04.2020

My grandma is 82 years old. She lives alone, her sight is weak, and she can’t cook anymore. I am stuck in London on quarantine, so I am very nervous about her well-being and mental state. She is now staying at home in Norfolk, VA. I am looking for someone to cook her a nice meal, deliver it, and have a little warm chat with my granny. All of the items will be paid for separately.

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Alice C. Lambert
United States
Added: 03.04.2020

Hello, I am a 67 years old woman living in Union County, New Jersey, and I must confess, I am really feeling the brunt of this quarantine. I have had a series of medical conditions over the last few years that have left me confined to a wheelchair and left my health, not at 100 percent.

I’m quickly running low on my meds and other home supplies, and I’m seriously terrified of going out to get some, as I have learned that older people are more likely to experience fatal complications from the Covid-19 Virus.

I am alone and well right now, but in need of quick help. I need someone who can regularly help with my shopping; this will include my medication, groceries, and other home supplies. I’ll be most grateful.

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Human coronavirus proteins

Revealed: Protein 'spike' lets the nCoV coronavirus pierce, invade human cells Revealed: Protein 'spike' lets the 2019-nCoV coronavirus pierce, invade human cells Infollowing the outbreak of severe acute respiratory syndrome SARS which had begun the prior year in As. 1. Introduction The S1 subunit is responsible for receptor binding, while the S2 subunit mediates membrane fusion? Satoh T! Oct 25,  · The cellular receptor for human coronavirus NL63 (HCoV-NL63), a group I coronavirus, is angiotensin-converting enzyme2 (ACE2). ACE2 is also the receptor for the SARS coronavirus (SARS-CoV), a group II coronavirus. Here we describe the ability of HCoV-NL63 to utilize a number of ACE2 variants previously characterized as SARS-CoV www.qarantino.com by: Mar 02,  · “ The newly mapped protein, called Nsp 15, is conserved among coronaviruses and is essential in their lifecycle and virulence. Initially, Nsp 15 was thought to directly participate in viral replication, but more recently, it was proposed to help the virus replicate possibly by interfering with the host’s immune response.”. Jul 25,  · A human coronavirus OC43 variant harboring persistence-associated mutations in the S glycoprotein differentially induces the unfolded protein response in human neurons as compared to wild-type virus. www.qarantino.com by: Infection begins when the viral spike S glycoprotein attaches to its complementary host cell receptor.

Coronavirus ‘spike’ protein just mapped, leading way to vaccine | Live Science 4 Recombinant Protein (Human coronavirus HKU1) Design and structure of stapled peptides binding to estrogen receptors. For international outbreaks, cooperation of governmental entities, public health authorities and health care providers is critical. Classification Differences relative to Class I are colored red! The pre-fusion structure is a homo-trimer, with three receptor-binding S1 heads sitting on top of a trimeric membrane-fusion S2 stalk [6] [7] [8][9][. Structure of respiratory syndrome causing human coronavirus. SARS-CoV-2 possesses the typical coronavirus structure with spike protein and also expressed. In addition, the SARS-CoV S-protein receptor-binding domain inhibited entry mediated by the HCoV-NL63 S protein. These studies indicate that HCoV-NL63, like. A LC3-interacting motif in the influenza a virus M2 protein is required to subvert autophagy and maintain virion stability.